Despised and Rejected. Isaiah 52:13--53:3

Isaiah 53:3 (Amplified Bible)

3He was despised and rejected and forsaken by men, a Man of sorrows and pains, and acquainted with grief and sickness; and like One from Whom men hide their faces He was despised, and we did not appreciate His worth or have any esteem for Him.

Can NT believers despise Him?  Can we not appreciate His worth (despise) or NOT have any esteem for Him?

I believe NT believers can (in a way) despise when we hear His voice, but do NOT or even delay in obeying. We’re NOT giving His unction (in our spirit) value and we esteem Him not (KJV).